This book is designed to provide mail centre managers, their supervisors, and an organisation’s security personnel a framework for understanding and mitigating risks posed to the organisation by the mail and packages it receives and delivers on a daily basis. A wide range of potential threats can be introduced into an organisation by way of the mail centre. Threats that involve chemical, biological, radiological, nuclear, or explosive substances are both dangerous and disruptive. Some threats, such as white powder hoaxes and threatening letters, are merely designed to disrupt the activities of an organisation or to express dissatisfaction with a particular individual or policy. The mail centre screening and handling processes must be able to identify threats and hoaxes and eliminate or mitigate the risk they pose to the organisation, its employees, and daily operations. This book provides an introduction to and understanding of the most efficient and effective processes and procedures to handle and screen mail entering an organisation’s mail processing facilities.