A plague sweeps through Jacksonville in Northern Europe. Virtually everyone in the city is temporarily disabled, even hospitalized. Everyone except a small number of ‘reverse effect’ people. These people seem to benefit. The International Investigation Agency sends its top agents to track down the problem–but their activities seem hampered–as if someone in the trusted upper reaches of the Agency was sabotaging, even betraying them. A billionaire businessman, his too-beautiful mistress, the coldblooded inspector, the hotheaded deputy of the Agency, and a mysterious doctor all become suspects, players, and possible victims as the Internationa Investigation Agency does its best to track down the truth.