When Stephen Wolfram's groundbreaking A New Kind of Science was published in 2002, its exploration and analysis of the computational universe of simple programs launched a scientific revolution. Twenty years later, the ideas and results of the book have found countless applications across science, technology and elsewhere - including the recent Wolfram Physics Project and its breakthrough in fundamental physics - and the book has indeed spawned what can only be described as a new kind of science. Here Wolfram reflects on the first two decades of A New Kind of Science, discussing some of the major implications that have emerged so far, as well as his far-reaching new thinking building on the conceptual framework developed in A New Kind of Science. Written in Wolfram's popular and accessible style, the book provides a window into one of the most vibrant intellectual developments of our time.Recognizing A New Kind of Science's significance not only in science but also in the arts, the book includes a gallery of pieces created over the past 20 years by artists inspired by the book.