The chapters in Foundations of Biosocial Health: Stigma and Illness Interactions, drawn primarily from medical anthropology, highlight the diverse ways in which various stigmatized health conditions interact with social inequalities and stigma to form syndemics. The authors delineate multiple examples of stigma-driven syndemics to demonstrate both the nature of disease interactions and how stigma contributes to, promotes, exacerbates, or perpetuates a syndemic. In so doing, the authors also address how stigma translates from a social condition to various biological conditions. The authors’ contributions cover a variety of topics, including HIV, substance use, obesity, depression, homelessness, poverty,and political oppression. This book is recommended for scholars of anthropology, sociology, psychology, political science, and public health.