Insertional Mutagenesis Strategies in Cancer Genetics

Insertional Mutagenesis Strategies in Cancer Genetics
Format
Hardback
Publisher
Springer-Verlag New York Inc.
Country
United States
Published
19 November 2010
Pages
200
ISBN
9781441976550

Insertional Mutagenesis Strategies in Cancer Genetics

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The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.

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