Purchase of this book includes free trial access to www.million-books.com where you can read more than a million books for free. This is an OCR edition with typos. Excerpt from book: PART FIRST ANATOMO-PATHOLOGIC STUDY Chronic gonorrheal urethritis results from the evolution of lesions produced by the gonocoecus upon the urethral mucosa. It succeeds directly upon the clap, when the acute phenomena have become ameliorated and when the disease takes on a slow course, which may become indefinitely prolonged. This passage into the chronic form is well defined, from an anatomic point of view, by the appearance of connective-tissue fibers at the seat of parvicellular infiltration, which invades the mucosa during the acute form. These changes appear after a variable lapse of time, generally toward the end of the second month of the disease; but they may also be retarded or show themselves much later. In other respects they do not correspond to a well-defined modification of the symptoms, because they do not appear at the same instant in the whole extent of the canal; they make their d6bnt, on the contrary, in a few spots, only to become generalized little by little. It is thus that gonorrhea passes slowly and gradually from the acute into the chronic form; and from this fact it results that one can never precisely indicate the moment when chronic urethritis begins. To make the evolution of the disease clear, we will first briefly recall certain points in the anatomy of the normal urethra and the chief characteristics of the gonocoecus, which are indispensable; we will then investigate the characteristic lesions of acute gonorrheal urethritis and, finally, we will observe the alterations which the canal undergoes during the whole course of chronic urethritis. [The onset of chronic urethritis is not dependent upon the time which has elapsed since the acute attack, but upon the clinical symptoms which have developed after the acute attack has spent its fury…