The understanding of the principles of ICP-MS and its application as an analytical technique is continually evolving and this book provides a snapshot at the start of the new millennium. It covers a range of topics including the fate of the sample as it passes through the sample introduction system, chemical resolution using reaction and collision cells, various methods of mass analysis, approaches to account for spectral interferences, hyphenation methods to enable speciation, and the results of analyses ranging from natural waters and archaeological isotope ratios to organometallic speciation in biological materials. Describing explicitly the analytical methods that deal with analytical challenges, and offering a perspective on elemental analysis by plasma source mass spectrometry this book should be of use to academics and industrialists.