Genetic erosion, that is, the loss of native plant and genetic diversity has been exponential from the Mediterranean Basin through the 20th century. This careless eradication of species and genetic diversity as a result of human activities from a hot-spot of diversity threatens sustainable agriculture and food security for the temperate regions of the world. Since the early 1900s there has been a largely ad hoc movement to halt the loss of plant diversity and enhance its utilization. The Convention on Biological Diversity and Food and Agriculture Organization of the United Nations International Undertaking on Plant Genetic Resources, both highlight the need to improve conservation methodologies and enhance utilisation techniques. It has been argued that the most important component of biodiversity is the genetic diversity of crop and forage species used to feed humans and livestock. These cultivated and related wild species provides the raw material for further selection and improvement. Leguminosae species are of major economic importance (peas, chickpeas, lentils and faba beans, as well as numerous forage species) and provide a particularly rich source of protein for human and animal foods. Their distribution is concentrated in the Mediterranean region and therefore the improvement of their conservation and use in the region is critical. This text is designed to help ensure an adequate breadth of legume diversity is conserved and to help maximize the use of that conserved diversity. The subjects of conservation and use of legume diversity, the Mediterranean ecosystem and taxonomy of legumes are introduced. Generic reviews of the taxonomy, centre of diversity, ecogeographic distribution, genetic diversity distribution, conservation status, conservation gaps and future research needs are provided, along with a discussion of the importance of rhizobia to the maintenance of legume diversity. Current ex situ and in situ conservation activities as well current legume uses are reviewed. In conclusion future priorities for ex situ and in situ plant genetic conservation and use of Mediterranean legumes are highlighted. All contributors look forward rather than simply reviewing past and current activities and therefore it is hoped that the identification of genetic erosion, location of taxonomic and genetic diversity and promotion of more efficient utilization of conserved material will be enhanced.