Rachel Adina Salm, a Jewish-German dentistry student living in Munich, undergoes two monumental life changes over the course of two days in 1937. She is called home to Essen to say goodbye to her dying grandmother the night before Rosh Hashanah. In her last words, her grandmother bestows upon her a blue sapphire amulet. The following day Rachel delivers a daughter out of wedlock. She and the Protestant father, Otto, place the child in a cloister to shield her from the Nazis who have taken control of Germany.

Rachel and Otto settle into a normal life, but eventually the war catches up to them. He is drafted into service, and she is sent to a concentration camp. There she meets an SS officer who falls in love with her.

Will Rachel learn the fate of her husband? Will she, a Jewish woman, stay with an SS officer post-war? Will she ever reconnect with her daughter?

The Blue Sapphire Amulet depicts the story of three generations of women whose past, present, and future are linked by their connection to a singular piece of jewelry. More importantly, it is the story of a woman who falls in love with three unlikely suitors, illustrating how love can exist in the most unlikely places.