Leadership in innovation is essential to U.S. prosperity and security. In a global, knowledge-driven economy, technological innovation - the transformation of new knowledge into products, processes, and services of value to society - is critical to competitiveness, long-term productivity growth, and an improved quality of life. Preeminence in technological innovation depends on a wide array of factors, one of which is leadership in engineering research, education, and practice. A three decade- long decline in the share of federal investment in research and development devoted to engineering and a perceived erosion of basic, long-term engineering research capability in U.S. industry and federal laboratories have raised serious questions about the long-term health of engineering research in the United States. This book illustrates the critical role of engineering research in maintaining U.S. technological leadership; documents major challenges and opportunities facing the U.S. engineering research enterprise; and offers specific recommendations for leaders in federal and state government, industry, and universities to help strengthen U.S. engineering research in the face of intensifying global competition.