In the twenty-first century, the production and use of scientific knowledge is more regulated, commercialized, and participatory than at any other time. The stakes in understanding these changes are high for scientist and nonscientist alike: they challenge traditional ideas of intellectual work and property and have the potential to remake legal and professional boundaries and transform the practice of research. A critical examination of the structures of power and inequality these changes hinge upon, this book explores the implications for human health, democratic society, and the environment.