Table of Contents

Preface: Hyaluronan and Can cer Robert Stern

Sectio n I: Historical Overview

1.Associat ion between ?acid mucopolysaccharides? and malignancy: an old
concept comes of age, finally

Robert Ster n

Section II: Cell Biology of Hyalu ronan in Cancer

2.Hyaluronan: a con stitutive regulator of chemoresistance and malignancy in cancer cells Mark G. Slomiany and Bryan P. Toole

3.Growth factor regulation of hyaluronan deposition in malignancies
Paraskevi Heldin, Eugenia Karousou, and Spyros S. Skandali s

4.HYALURONAN BINDING PROTEIN 1 (HABP1) IN C ANCER BIOLOGY Kasturi Datta

Section III: Hyaluronan Receptors and Signal Transduction Path ways

5.CD44 meets merlin and ezrin: Their interplay mediates the pro-tumor activity of CD44 and tumor-suppr