Arranged in chronological order from the early Greek mathematicians, Euclid and Archimedes through to present-day Nobel Prize winners, 100 Science Discoveries That Changed the World charts the great breakthroughs in scientific understanding.
Each entry describes the story of the research, the significance of the science and its impact on the scientific world. There is also a resume of each scientist’s career along with their other achievements, sometimes - in the case of Isaac Newton - in a completely unrelated field (laws of motion and the component parts of light).

The book covers all branches of science: geometry, number theory, cosmology, the laws of motion, particle physics, electricity, magnetism, the laws of gasses, optical theory, cell biology, conservation of energy, natural selection, radiation, quantum theory, special relativity, superconductivity, thermodynamics, genomes, plate tectonics, and the uncertainty principal.

Scientists include: Albert Einstein, Alessandro Volta, Alexander Fleming, Amedeo Avogrado, Andre Geim, Antoine Lavoisier, Antony van Leeuwenhoek, Archimedes, Benoit Mandelbrot, Carl Friedrich Gauss, Charles Darwin, Christian Doppler, Copernicus, Crick and Watson, Dmitri Mendeleev, Edwin Hubble, Enrico Fermi, Ernest Rutherford, Erwin Schrodinger, Euclid, Fermat, Frederick Sanger, Galileo Galilei, Georg Ohm, Georges Lemaitre, Heike Kamerlingh, Isaac Newton, Jacques Charles, James Clerk Maxwell, James Prescott Joule, Jean Buridan, Johanes Kepler, John Ambrose Fleming, John Dalton, John O'Keefe, Joseph Black, Josiah Gibbs, Lord Kelvin, Lord Rayleigh, Louis Pasteur, Marie Curie, Martinus Beijerinck, Michael Faraday, Murray Gell-Mann & George Zweig, Neils Bohr, Nicholas Steno, Peter Higgs, Pierre Curie, Ptolemy, Robert Boyle, Robert Brown, Robert Hooke, Roger Bacon, Rudolf Clausius, Seleucus, Shen Kuo, Stanley Miller, Tyco Brahe, Werner Heisenberg, William Gilbert, William Harvey, William Herschel, William Rontgen, Wolfgang Pauli.