Huntington’s is a fairly devastating neuro-degenerative disease. This condition is well studied and is, at present, incurable. It is a brain disorder that damages some specific types of neurons, leading to degeneration in several parts of the brain causing them to lose their function. This results in uncontrolled movements, loss of intellectual abilities and behavioral disturbances. Since the mutation causes have been discovered, there have been several important advancements in understanding the cellular and molecular agitations. This book consists of current knowledge on a wide variety of issues involving this disease. It will help clinicians, health care providers, researchers and graduate students to enhance their understanding and knowledge about the clinical correlates, genetic issues, neuropathological findings, cellular and molecular events and potential therapeutic interventions involved in Huntington’s disease. This book not only showcases analyzed fundamental knowledge on the disease but also displays original research in various areas, which together, gives an inclusive description of the important issues in the area.