This second volume in the history of the McGill University Medical School begins a few years before the opening of the Royal Victoria Hospital in 1894 and traces the major developments in the institution’s second half century. At the beginning of this period the McGill Faculty of Medicine was already ranked as among the best in North America, but its reputation had declined by World War I. During the next twenty years major reforms created new research laboratories, expanded library facilities, and continued modernization of the Royal Victoria Hospital. The Montreal Neurological Institute was opened, a children’s hospital was established, and the Montreal General Hospital was expanded.