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This book covers key rodent models in studying diabetes. The first 8 chapters of the book are dedicated to the STZ-diabetic rat (the most widely used type I model of diabetes). This model has been used extensively to study molecular and cellular etiology of diabetes, the chronic complications of diabetes, and the effectiveness of anti-diabetic drugs. Chapters 9 through 12 discuss other models of type I diabetes and type II. The contributors are invited from top universities in Canada, the U.S.A. and Japan to provide an internationally oriented approach to this worldwide issue. External and internal reviews developed by the editor and contributors ensure the correct, clear, and concise presentation of the topics covered. Experimental Models of Diabetes will be an invaluable resource to every diabetes researcher in academia and industry.
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This book covers key rodent models in studying diabetes. The first 8 chapters of the book are dedicated to the STZ-diabetic rat (the most widely used type I model of diabetes). This model has been used extensively to study molecular and cellular etiology of diabetes, the chronic complications of diabetes, and the effectiveness of anti-diabetic drugs. Chapters 9 through 12 discuss other models of type I diabetes and type II. The contributors are invited from top universities in Canada, the U.S.A. and Japan to provide an internationally oriented approach to this worldwide issue. External and internal reviews developed by the editor and contributors ensure the correct, clear, and concise presentation of the topics covered. Experimental Models of Diabetes will be an invaluable resource to every diabetes researcher in academia and industry.