What happens when people with HIV apply to settle in Canada? Screening Out takes readers through the process of seeking permanent residency, demonstrating how mandatory HIV testing and the medical inadmissibility regime are organized to make such applications impossible. This ethnographic inquiry into the medico-legal and administrative practices governing the Canadian immigration system shows how it works from the perspective of the very people toward whom this exclusionary health policy is directed. Laura Bisaillon provides a vital corrective to state claims about mandatory HIV screening, pinpointing how and where things need to change.