Pharmacodynamics and Drug Development: Perspectives in Clinical Pharmacology

In recent years it has become clear that early information about pharmacodynamics leads to more efficient trial designs and improved clinical guidelines for the use of all drugs. Spanning many of the major drug classes, this book offers the essential facts and concepts and includes an authoritative section on general methodology and regulatory issues. The molecular biology and pharmacology of major receptor types are considered, as is the detailed pharmacodynamics of a wide range of therapeutic drug classes. The book will be of interest to researchers, clinical pharmacologists, physicians and regulators working in academia as well as the pharmaceutical industry worldwide.